Carbohydrate are essential for the metabolism of Fat.

*For complete oxidation of fatty acids , we need oxaloacetate. Fatty acids are broken down in to Acetyl CoA by beta oxidation. For oxidation to occur it needs oxaloacetate which is derived from carbohydrate metabolism.

  • acetyl CoA requires oxaloacetate to enter into TCA cycle
  • Glucose → Pyruvate → Oxaloacetate (via pyruvate carboxylase)

* If carbohydrate ids deficient , then oxaloacetate which is generated is diverted to gluconeogenesis. Thus there will be less Oxaloacetate available for TCA cycle, and Acetyl CoA cant be fully oxidized. *Thus there will be accumulation of Acetyl CoA and it will be directed to ketogenesis. *Also carbohydrates provide glycerol-3-phosphate through glycolysis.

  • -Glycerol-3-phosphate is essential for:
  • Esterification of fatty acids
  • Formation of triglycerides

*Without carbohydrates, fatty acids cannot be properly stored as triglycerides.

  • carbohydrate_are_essential_for_the_metabolism_of_fat.txt
  • Last modified: 2025/12/30 06:03
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