Show pageOld revisionsBacklinksBack to top This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong. **Cigratte smokes is injurious to health of lungs.** *Cigrarette smokes contains high concentration of free radicals( reactive nitrogen species, reactive oxygen species(ROS)) , which leads to intrease oxidative and nitrosative stress on lungs . * Lipid peroxidation of cell membrane thus damage to alveolar epithelium * ROS oxidize methionine residue of α₁-antitrypsin ------->α₁-antitrypsin becomes inactive *↓ Anti-protease activity → ↑ elastase activity-Elastase digests alveolar elastic tissue * Results in: Loss of lung elasticity, alveolar wall destruction. cigratte_smokes_is_injurious_to_health_of_lungs.txt Last modified: 2025/12/30 05:59by admin