Differences
This shows you the differences between two versions of the page.
| — |
cigratte_smokes_is_injurious_to_health_of_lungs [2025/12/30 05:59] (current) admin created |
||
|---|---|---|---|
| Line 1: | Line 1: | ||
| + | **Cigratte smokes is injurious to health of lungs.** | ||
| + | *Cigrarette smokes contains high concentration of free radicals( reactive nitrogen species, reactive oxygen species(ROS)) , which leads to intrease oxidative and nitrosative stress on lungs . | ||
| + | |||
| + | * Lipid peroxidation of cell membrane thus damage to alveolar epithelium | ||
| + | * ROS oxidize methionine residue of α₁-antitrypsin -------> | ||
| + | *↓ Anti-protease activity → ↑ elastase activity-Elastase digests alveolar elastic tissue | ||
| + | * Results in: Loss of lung elasticity, alveolar wall destruction. | ||