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carbohydrate_are_essential_for_the_metabolism_of_fat [2025/12/30 06:03] (current) admin created |
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| + | **Carbohydrate are essential for the metabolism of Fat.** | ||
| + | *For complete oxidation of fatty acids , we need oxaloacetate. Fatty acids are broken down in to Acetyl CoA by beta oxidation. For oxidation to occur it needs oxaloacetate which is derived from carbohydrate metabolism. | ||
| + | * acetyl CoA requires oxaloacetate to enter into TCA cycle | ||
| + | | ||
| + | * If carbohydrate ids deficient , then oxaloacetate which is generated is diverted to | ||
| + | gluconeogenesis. Thus there will be less Oxaloacetate available for TCA cycle, and Acetyl CoA cant be fully oxidized. | ||
| + | *Thus there will be accumulation of Acetyl CoA and it will be directed to ketogenesis. | ||
| + | *Also carbohydrates provide glycerol-3-phosphate through glycolysis. | ||
| + | *-Glycerol-3-phosphate is essential for: | ||
| + | *Esterification of fatty acids | ||
| + | *Formation of triglycerides | ||
| + | *Without carbohydrates, | ||